Description

4-Benzyl-2-(Hydroxymethyl)Homomorpholine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for constructing complex molecular architectures, particularly in medicinal chemistry programs targeting neurological and cardiovascular diseases.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular therapeutics.
• Asymmetric Synthesis: Employed as a building block or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the exploration of new pharmacophores due to its morpholine core and functional handles.
• Fine Chemical Production: Serves as a starting material for the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Academic & Industrial R&D: Utilized in research institutions and corporate labs for developing new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	4-Benzyl-2-(Hydroxymethyl)Homomorpholine
CAS No.	1031442-66-6
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	2-(Hydroxymethyl)-4-benzylhomomorpholine; 4-Benzyl-2-(hydroxymethyl)homomorpholine; 4-Benzyl-2-(hydroxymethyl)hexahydro-1,4-oxazepine; Homomorpholine, 4-benzyl-2-(hydroxymethyl)-; (4-Benzylhexahydro-1,4-oxazepin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our 4-Benzyl-2-(Hydroxymethyl)Homomorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.