Description

Ethyl cis-n-Boc-3-Phenylpiperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, particularly for projects targeting central nervous system (CNS) disorders and other therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• API Development: Serves as a protected precursor in the production of active pharmaceutical ingredients, especially those with piperidine-based pharmacophores.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for the study of organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl cis-n-Boc-3-Phenylpiperidine-4-Carboxylate
CAS No.	1027710-05-9
Molecular Formula	C19H27NO4
Molecular Weight	333.43 g/mol
Synonyms	Ethyl cis-1-(tert-Butoxycarbonyl)-3-phenylpiperidine-4-carboxylate; 1-Boc-3-phenyl-4-piperidinecarboxylic acid ethyl ester (cis); cis-1-N-Boc-3-phenylpiperidine-4-carboxylic acid ethyl ester; 4-Piperidinecarboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-3-phenyl-, ethyl ester, cis-; Ethyl 1-Boc-3-phenylpiperidine-4-carboxylate (cis); cis-3-Phenyl-1-Boc-piperidine-4-carboxylic acid ethyl ester; BOC-3-Phenyl-piperidine-4-carboxylic acid ethyl ester (cis)
EINECS	Contact for details

Quality Control

Our Ethyl cis-n-Boc-3-Phenylpiperidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.