Description

2-Bromo-5-(1H-Pyrrol-1-Yl)Pyrazine is a high-value, functionalized heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for medicinal chemistry and materials science research, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and specialty chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its pyrazine core for biological activity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Used to develop molecular probes and tags for studying biological processes and target engagement.
• Academic & Contract Research: Essential for synthetic methodology development and exploring new chemical space in academic and CRO laboratories.

Basic Information

Item	Details
Product Name	2-Bromo-5-(1H-Pyrrol-1-Yl)Pyrazine
CAS No.	1027512-24-8
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	2-Bromo-5-(pyrrol-1-yl)pyrazine; 2-Bromo-5-(1H-pyrrol-1-yl)pyrazine; 1027512-24-8; 5-(1H-Pyrrol-1-yl)-2-bromopyrazine; 2-Bromo-5-pyrrol-1-ylpyrazine; Pyrrole, 1-(5-bromo-2-pyrazinyl)-; 1-(5-Bromo-2-pyrazinyl)-1H-pyrrole
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(1H-Pyrrol-1-Yl)Pyrazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.