Description

4-[[(1R)-3-(4-Morpholinyl)-1-[(Phenylthio)Methyl]Propyl]Amino]-3-Trifluoromethylsulfonyl-Benzenesulfonamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern drug discovery programs. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions focused on developing novel therapeutic agents, particularly in areas requiring sophisticated sulfonamide and morpholine-based chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization, particularly for targets involving sulfonamide pharmacophores.
• Protease Inhibitor Development: Potential building block for the synthesis of inhibitors targeting specific enzymes, given the presence of the trifluoromethylsulfonyl and benzenesulfonamide groups.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and protein function.
• Process Chemistry & Scale-Up: Supports route scouting and process development for the efficient, scalable production of candidate drugs.
• Academic & Institutional Research: Employed in synthetic organic chemistry research to explore new reactions and methodologies involving complex amines and sulfonamides.

Basic Information

Product Name	4-[[(1R)-3-(4-Morpholinyl)-1-[(Phenylthio)Methyl]Propyl]Amino]-3-Trifluoromethylsulfonyl-Benzenesulfonamide
CAS No.	1027345-12-5
Molecular Formula	C21H24F3N3O5S3
Molecular Weight	543.62 g/mol
Synonyms	4-[(1R)-3-Morpholin-4-yl-1-(phenylsulfanylmethyl)propylamino]-3-(trifluoromethylsulfonyl)benzenesulfonamide; Benzenesulfonamide, 4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-(trifluoromethylsulfonyl)-; (R)-4-(3-Morpholino-1-((phenylthio)methyl)propylamino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide; CAS 1027345-12-5
EINECS	Contact for details

Quality Control

Our 4-[[(1R)-3-(4-Morpholinyl)-1-[(Phenylthio)Methyl]Propyl]Amino]-3-Trifluoromethylsulfonyl-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing specifications such as HPLC purity, chiral purity, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.