Description

m-Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) and a key pharmaceutical intermediate. Its primary commercial value lies in its role as a precursor in the synthesis of the active pharmaceutical ingredient Loxoprofen, a widely used analgesic and anti-inflammatory agent. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring high-purity building blocks for API production.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of the API Loxoprofen Sodium.
• Analgesic Drug Development: Serves as a key starting material in R&D for novel NSAID formulations and prodrugs.
• Reference Standard: Used as a high-purity chemical reference standard in quality control laboratories for analytical method development and validation.
• Process Chemistry: Employed in scale-up and optimization studies within fine chemical and contract manufacturing organizations (CMOs).
• Academic & Industrial Research: Utilized in pharmacological studies to investigate the structure-activity relationships of profen-class anti-inflammatory agents.

Basic Information

Product Name	m-Loxoprofen
CAS No.	1026471-88-4
Molecular Formula	C15H18O3
Molecular Weight	246.30 g/mol
Synonyms	2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propanoic Acid; (±)-2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid; Loxoprofen Related Compound; Loxoprofen Intermediate; m-Loxoprofen Acid; Loxoprofen Free Acid; UNII-8V5Q8B8QCL (component); Loxoprofen (unconjugated form)
EINECS	Contact for details

Quality Control

Our m-Loxoprofen is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) is supplied with each batch, detailing purity, identity, and impurity profiles as determined by validated analytical methods including HPLC, IR, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.