Description

Resolvin D4 is a specialized pro-resolving lipid mediator (SPM) derived from the ω-3 fatty acid docosahexaenoic acid (DHA). This compound plays a critical role in the active resolution of inflammation, offering a targeted mechanism distinct from conventional immunosuppression. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on advanced inflammation resolution, immunology, and metabolic research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the molecular mechanisms of inflammation resolution.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore for developing novel therapeutics targeting chronic inflammatory diseases.
• In Vitro & In Vivo Studies: Applied in cellular assays and animal models to elucidate the biological functions and signaling pathways of specialized pro-resolving mediators (SPMs).
• Metabolic Disorder Research: Investigated for its potential role in modulating inflammation associated with metabolic syndromes.
• Analytical Standard: Employed as a high-purity standard in LC-MS, HPLC, and other analytical methods for quantitative and qualitative analysis in biological matrices.

Basic Information

Product Name	Resolvin D4
CAS No.	1025684-60-9
Molecular Formula	C22H32O5
Molecular Weight	376.49 g/mol
Synonyms	RvD4; (4Z,7S,8E,10E,12Z,14E,16S,17S,19Z)-7,8,17-Trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid; 7(S),8(S),17(S)-Trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid; Resolvin D4 (RvD4); PD1n-3 DPA; Specialized Pro-resolving Mediator D4
EINECS	Contact for details

Quality Control

Our Resolvin D4 is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is supported by comprehensive analytical data, including HPLC purity, LC-MS confirmation, and NMR structural verification. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.