Description

(1-Isopropyl-3-Oxo-Piperazin-2-Yl)-Acetic Acid is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced organic synthesis. Its value lies in its piperazinone core, which serves as a privileged scaffold for constructing complex molecules with potential biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially those targeting the central nervous system (CNS) or infectious diseases.
• Agrochemical Synthesis: Used in the development of novel, high-performance pesticides and herbicides, leveraging its complex heterocyclic structure.
• Peptidomimetics Research: Serves as a constrained, non-proteinogenic amino acid analog for designing peptide mimics with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the synthesis of specialized molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Used in university and institutional labs for methodological development in asymmetric synthesis and medicinal chemistry studies.

Basic Information

Item	Detail
Product Name	(1-Isopropyl-3-Oxo-Piperazin-2-Yl)-Acetic Acid
CAS No.	1024618-84-5
Molecular Formula	C9H16N2O3
Molecular Weight	200.24 g/mol
Synonyms	2-(1-Isopropyl-3-oxopiperazin-2-yl)acetic acid; (1-Isopropyl-3-oxo-2-piperazinyl)acetic Acid; 1-Isopropyl-3-oxopiperazine-2-acetic acid; (R/S)-(1-Isopropyl-3-oxo-piperazin-2-yl)-acetic acid; 1024618-84-5; UNII-8V8Y1F4Q4F; 8V8Y1F4Q4F; SCHEMBL2180621; AKOS040759626; F2191-6471
EINECS	Contact for details

Quality Control

Every batch of (1-Isopropyl-3-Oxo-Piperazin-2-Yl)-Acetic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our standard quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.