Description

Ethyl 4-((2,6-Difluorophenyl)Carbonyl)Piperazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine and difluorophenyl structural motifs. This compound is of significant value in modern synthetic organic chemistry, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its role in constructing complex molecules with potential therapeutic and biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the difluorophenyl group.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions in biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential raw material for CDMOs (Contract Development and Manufacturing Organizations) engaged in producing tailored compounds for client R&D programs.
• Library Synthesis for Drug Discovery: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening against novel biological targets.

Basic Information

Product Name	Ethyl 4-((2,6-Difluorophenyl)Carbonyl)Piperazinecarboxylate
CAS No.	1024523-06-5
Molecular Formula	C14H16F2N2O3
Molecular Weight	298.29 g/mol
Synonyms	Ethyl 1-[(2,6-difluorophenyl)carbonyl]piperazine-4-carboxylate; 4-Carbethoxy-1-(2,6-difluorobenzoyl)piperazine; 1-(2,6-Difluorobenzoyl)-4-(ethoxycarbonyl)piperazine; Piperazine-1-carboxylic acid, 4-[(2,6-difluorobenzoyl)]-, ethyl ester; Ethyl 4-(2,6-difluorobenzoyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-((2,6-Difluorophenyl)Carbonyl)Piperazinecarboxylate is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical R&D. Our quality control protocols include identity confirmation, purity assay, and impurity profiling using advanced techniques. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.