Description

1-Piperazinecarboxylic Acid, 4-(4-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-value pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its core value proposition lies in its role as a protected precursor for the piperazine pharmacophore, enabling the efficient development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors focused on drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• API Synthesis: Used in the research, development, and scale-up production of new Active Pharmaceutical Ingredients (APIs), where its protected amino and carboxylic acid groups offer strategic synthetic advantages.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Route Scouting: Employed by process chemists to develop efficient, scalable, and cost-effective synthetic routes for candidate drugs.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and manufacturing services for the global pharmaceutical industry.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(4-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1023594-50-4
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	tert-Butyl 4-(4-amino-3-pyridinyl)piperazine-1-carboxylate; 4-(4-Amino-3-pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 4-(4-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; BOC-4-(4-Amino-3-pyridinyl)piperazine; N-Boc-4-(4-amino-3-pyridinyl)piperazine; 1023594-50-4; tert-Butyl 4-(4-aminopyridin-3-yl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxylic Acid, 4-(4-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and manufacturing applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.