Description

1-Boc-4-(3-Amino-4-Pyridinyl)-Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine core linked to an amino-substituted pyridine. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the development of new therapeutic agents, particularly in oncology and CNS drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors and receptor modulators.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker component connecting E3 ligase ligands to target protein binders.
• Chemical Biology Research: Used in the design and construction of molecular probes for studying protein-protein interactions and cellular signaling pathways.
• Agrochemical Synthesis: Potential intermediate for creating new active ingredients with specific biological activity.
• Academic & Contract Research: Employed in university and CRO settings for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	1-Boc-4-(3-Amino-4-Pyridinyl)-Piperazine
CAS No.	1023298-54-5
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-4-(3-Amino-4-pyridyl)piperazine; tert-Butyl 4-(3-amino-4-pyridinyl)-1-piperazinecarboxylate; 4-(3-Amino-4-pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(3-amino-4-pyridinyl)piperazine; 1023298-54-5; BOC-4-(3-AMINO-4-PYRIDINYL)-PIPERAZINE
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(3-Amino-4-Pyridinyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.