Description

n-(4-Methoxyphenyl)Pyrazin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazine core substituted with an aniline derivative. This compound is of significant commercial interest due to its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions to construct more complex heterocyclic frameworks.
• Agrochemical Research: Employed in the development of new crop protection agents and herbicides due to its bioactive pyrazine structure.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or optical properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical research and method development.

Basic Information

Product Name	n-(4-Methoxyphenyl)Pyrazin-2-Amine
CAS No.	1022128-78-4
Molecular Formula	C11H11N3O
Molecular Weight	201.23 g/mol
Synonyms	2-Pyrazinamine, N-(4-methoxyphenyl)-; 4-Methoxy-N-(pyrazin-2-yl)aniline; N-(4-Methoxyphenyl)pyrazin-2-amine; 2-(4-Methoxyanilino)pyrazine; p-Methoxyphenylpyrazin-2-amine; 1022128-78-4
EINECS	Contact for details

Quality Control

Our n-(4-Methoxyphenyl)Pyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.