Description

4-[2-(Aminomethyl)Phenyl]-2-Piperazinone is a specialized organic compound featuring a piperazinone core linked to an ortho-aminomethyl phenyl group. This unique bifunctional structure makes it a valuable pharmaceutical intermediate and building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) due to its versatile piperazinone pharmacophore.
• Chemical Synthesis: Serves as a precursor for creating libraries of compounds for high-throughput screening (HTS) in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research-scale and pilot-scale production of potential therapeutic agents.
• Bioconjugation & Probe Synthesis: The aminomethyl group allows for functionalization, making it suitable for creating labeled compounds or molecular probes.

Basic Information

Item	Details
Product Name	4-[2-(Aminomethyl)Phenyl]-2-Piperazinone
CAS No.	1021236-94-1
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	2-Piperazinone, 4-[2-(aminomethyl)phenyl]-; 4-(2-Aminobenzyl)piperazin-2-one; 1-(2-Aminobenzyl)piperazine-2,3-dione (tautomer); 4-(2-Aminomethylphenyl)-2-piperazinone; 1021236-94-1; 4-(2-Aminobenzyl)-2-piperazinone; 2-Piperazinone, 4-[2-(aminomethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 4-[2-(Aminomethyl)Phenyl]-2-Piperazinone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.