Description

(5S,6E,8Z)-5,18-Dihydroxy-6,8-Octadecadienoic Acid is a specialized, high-purity hydroxy fatty acid derivative with a defined stereochemistry. This compound is valued for its role as a key synthetic intermediate and a potential bioactive molecule in advanced research and development. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for the synthesis of complex molecules, including prostaglandin analogs and other lipid mediators.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of prostaglandins, leukotrienes, and other eicosanoid-like bioactive compounds.
• Agrochemical Research: Used in the development of novel plant growth regulators or signaling molecule analogs due to its lipid-based structure.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies related to fatty acid metabolism and oxidation pathways.
• Cosmetic Science: Investigated for potential applications in advanced skincare formulations targeting specific cellular pathways.
• Organic Synthesis: Employed as a versatile intermediate in stereoselective synthesis for introducing specific hydroxy and diene functionalities.
• Material Science: Potential monomer for creating specialized polymers with unique properties derived from its bifunctional nature.

Basic Information

Product Name	(5S,6E,8Z)-5,18-Dihydroxy-6,8-Octadecadienoic Acid
CAS No.	1021188-24-8
Molecular Formula	C₁₈H₃₂O₄
Molecular Weight	312.44 g/mol
Synonyms	5,18-Dihydroxy-6,8-octadecadienoic acid; (5S,6E,8Z)-5,18-Dihydroxyoctadeca-6,8-dienoic acid; 5S,18-Dihydroxy-6E,8Z-octadecadienoic acid; Octadecadienoic acid, 5,18-dihydroxy-6,8-; Lipid mediator intermediate; Hydroxyoctadecadienoic acid (HODE) isomer
EINECS	Contact for details

Quality Control

Every batch of (5S,6E,8Z)-5,18-Dihydroxy-6,8-Octadecadienoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your R&D and cGMP needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (5S)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.