Description

1-Piperidinecarboxylic Acid, 4-[[3-[[5-(Trifluoromethyl)-2-Pyridinyl]Oxy]Phenyl]Methylene]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular architecture incorporating piperidine, trifluoromethylpyridine, and a tert-butyl ester group. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, especially within oncology and central nervous system (CNS) research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly for targeted therapies.
• API Development: Used in research and development for constructing complex molecular scaffolds in potential oncology and CNS disorder treatments.
• Chemical Biology Research: Employed as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of investigational new drugs.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for pioneering synthetic methodology and novel compound library generation.

Basic Information

Item	Details
Product Name	1-Piperidinecarboxylic Acid, 4-[[3-[[5-(Trifluoromethyl)-2-Pyridinyl]Oxy]Phenyl]Methylene]-, 1,1-Dimethylethyl Ester
CAS No.	1020325-45-4
Molecular Formula	C24H25F3N2O3
Molecular Weight	446.47 g/mol
Synonyms	tert-Butyl 4-{[3-({[5-(trifluoromethyl)pyridin-2-yl]oxy})phenyl]methylene}piperidine-1-carboxylate; 4-((3-((5-(Trifluoromethyl)pyridin-2-yl)oxy)benzylidene)piperidine-1-carboxylic acid tert-butyl ester; BOC-protected trifluoromethylpyridine-piperidine intermediate; (E/Z)-tert-Butyl 4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzylidene)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-[[3-[[5-(Trifluoromethyl)-2-Pyridinyl]Oxy]Phenyl]Methylene]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and should be handled under inert atmosphere if found to be easily oxidized. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.