Description

5-Bromo-3-Nitro-2-(Pyrrolidin-1-Yl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Catalyst Ligand Synthesis: Utilized to create novel nitrogen-donor ligands for transition metal catalysis in fine chemical manufacturing.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	5-Bromo-3-Nitro-2-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1020253-22-8
Molecular Formula	C9H10BrN3O2
Molecular Weight	272.10 g/mol
Synonyms	2-(Pyrrolidin-1-yl)-5-bromo-3-nitropyridine; 5-Bromo-3-nitro-2-(1-pyrrolidinyl)pyridine; 5-Bromo-2-pyrrolidin-1-yl-3-nitropyridine; Pyridine, 5-bromo-3-nitro-2-(1-pyrrolidinyl)-; 1020253-22-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Nitro-2-(Pyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.