Description

5-Chloro-3-Fluoro-N,n-Dimethylpyridin-2-Amine Hydrochloride is a high-purity, synthetically valuable halogenated pyridine derivative. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and creating new heterocyclic compounds.
• Ligand and Catalyst Development: The dimethylamino group provides a coordination site, making it useful for synthesizing specialized ligands in catalytic systems.
• Material Science Precursor: Can be utilized in the synthesis of functionalized organic materials and specialty chemicals.

Basic Information

Item	Details
Product Name	5-Chloro-3-Fluoro-N,n-Dimethylpyridin-2-Amine Hydrochloride
CAS No.	1020253-19-3
Molecular Formula	C7H9ClFN2•HCl
Molecular Weight	209.52 (Free base) / 245.98 (Hydrochloride salt)
Synonyms	2-Amino-5-chloro-3-fluoro-N,N-dimethylpyridine hydrochloride; 5-Chloro-3-fluoro-N,N-dimethylpyridin-2-amine HCl; 5-Chloro-3-fluoro-2-(dimethylamino)pyridine hydrochloride; N,N-Dimethyl-5-chloro-3-fluoropyridin-2-amine hydrochloride; 1020253-19-3; 2-Pyridinamine, 5-chloro-3-fluoro-N,N-dimethyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluoro-N,n-Dimethylpyridin-2-Amine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.