Description

5-Chloro-3-Fluoro-2-(Pyrrolidin-1-Yl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for pharmaceutical and agrochemical research, serving as a key intermediate in the development of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the pyridine core for bioactivity.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Precursor: Can be utilized in the synthesis of specialized ligands for catalysis or functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Chloro-3-Fluoro-2-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1020253-18-2
Molecular Formula	C9H10ClFN2
Molecular Weight	200.64 g/mol
Synonyms	2-(Pyrrolidin-1-yl)-5-chloro-3-fluoropyridine; 5-Chloro-3-fluoro-2-(1-pyrrolidinyl)pyridine; 5-Chloro-3-fluoro-2-pyrrolidin-1-ylpyridine; 1020253-18-2; 2-Pyrrolidin-1-yl-5-chloro-3-fluoropyridine; Pyridine, 5-chloro-3-fluoro-2-(1-pyrrolidinyl)-; 5-Chloro-3-fluoro-2-pyrrolidinylpyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluoro-2-(Pyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development and commercial projects with material produced to meet cGMP and ISO standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.