Description

tert-Butyl4-(5-Chloro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is essential for medicinal chemistry research and development, particularly in the construction of complex heterocyclic molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Bioconjugation & Probe Synthesis: Utilized in the development of chemical probes and labeled compounds for biological assay development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	tert-Butyl4-(5-Chloro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate
CAS No.	1020056-95-4
Molecular Formula	C27H45ClN4O2Si
Molecular Weight	521.21 g/mol
Synonyms	1-Boc-4-(5-Chloro-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine; tert-Butyl 4-(5-chloro-1-((triisopropylsilyl))-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine-1-carboxylate; 1020056-95-4; 4-(5-Chloro-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-piperazinecarboxylic acid tert-butyl ester; 1-Boc-4-(5-chloro-1-TIPS-1H-pyrrolo[2,3-b]pyridin-4-yl)piperazine; TIPS-protected pyrrolopyridine piperazine Boc-carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(5-Chloro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.