Description

(4-Methylpiperazin-1-Yl)Piperidin-4-Yl-Methanone Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound is a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) for various therapeutic areas.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the development and commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Can be utilized in the creation of biochemical probes and targeted drug delivery systems due to its reactive functional groups.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	(4-Methylpiperazin-1-Yl)Piperidin-4-Yl-Methanone Dihydrochloride
CAS No.	1019852-03-9
Molecular Formula	C12H24Cl2N3O
Molecular Weight	309.25 g/mol
Synonyms	4-(4-Methylpiperazine-1-carbonyl)piperidine dihydrochloride; 1-(4-Piperidinyl)-2-(4-methyl-1-piperazinyl)ethanone dihydrochloride; 4-(4-Methylpiperazine-1-carbonyl)piperidine hydrochloride (1:2); (4-Methylpiperazin-1-yl)(piperidin-4-yl)methanone dihydrochloride; 4-(4-Methyl-1-piperazinylcarbonyl)piperidine dihydrochloride; 4-Piperidinecarboxylic acid, 4-methyl-1-piperazinyl-, dihydrochloride
EINECS	Contact for details

Quality Control

Our (4-Methylpiperazin-1-Yl)Piperidin-4-Yl-Methanone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.