Description

(6R,7R)-7-Amino-6-Hydroxy-6,7,8,9-Tetrahydro-2,9A-Diazabenzo[Cd]Azulen-1(2H)-One Hydrochloride is a high-purity, complex heterocyclic building block and advanced pharmaceutical intermediate. Its value lies in its specific stereochemistry and functional groups, making it a critical precursor in the synthesis of novel, targeted therapeutic agents. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing new active pharmaceutical ingredients (APIs) with complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales for new APIs.
• Contract Development and Manufacturing Organization (CDMO) Services: A critical material supplied to CDMOs engaged in custom synthesis and manufacturing of complex molecules for clinical trials and commercial supply.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis methodology and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	(6R,7R)-7-Amino-6-Hydroxy-6,7,8,9-Tetrahydro-2,9A-Diazabenzo[Cd]Azulen-1(2H)-One Hydrochloride
CAS No.	1019769-47-1
Molecular Formula	C₁₂H₁₄ClN₃O₂
Molecular Weight	267.71 g/mol
Synonyms	(6R,7R)-7-Amino-6-hydroxy-6,7,8,9-tetrahydro-2,9a-diazabenzo[cd]azulen-1(2H)-one hydrochloride; 6,7,8,9-Tetrahydro-2,9a-diazabenzo[cd]azulen-1(2H)-one, 7-amino-6-hydroxy-, hydrochloride, (6R,7R)-; (6R,7R)-7-Amino-6-hydroxy-1,2,6,7,8,9-hexahydro-2,9a-diazabenzo[cd]azulen-1-one hydrochloride; Advanced Pharmaceutical Intermediate 1019769-47-1; Chiral Diazabenzoazulenone Derivative
EINECS	Contact for details

Quality Control

Our (6R,7R)-7-Amino-6-Hydroxy-6,7,8,9-Tetrahydro-2,9A-Diazabenzo[Cd]Azulen-1(2H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.