Description

4-(3-Oxopiperazin-1-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazinone-benzonitrile hybrid structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drugs.
• Kinase Inhibitor Synthesis: Serves as a core scaffold in the construction of potential kinase inhibitors for cancer therapy.
• CNS Active Compound Research: Used in the design and synthesis of compounds targeting neurological disorders.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in probe development for target identification.
• Custom Synthesis & Contract Manufacturing: A starting material for custom API synthesis under cGMP or research-grade conditions.
• Academic & Industrial R&D: Facilitates exploratory chemistry in both academic laboratories and industrial R&D centers.

Basic Information

Product Name	4-(3-Oxopiperazin-1-Yl)Benzonitrile
CAS No.	1019601-14-9
Molecular Formula	C12H12N4O
Molecular Weight	228.25 g/mol
Synonyms	4-(3-Oxo-1-piperazinyl)benzonitrile; 1-(4-Cyanophenyl)-3-oxopiperazine; 4-(3-Oxopiperazin-1-yl)benzonitrile; 4-(3-Oxo-1-piperazinyl)benzonitrile; 1019601-14-9; 4-(3-Oxopiperazin-1-yl)phenyl cyanide; 1-(4-Cyanophenyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Our 4-(3-Oxopiperazin-1-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.