Description

2-[4-(Trifluoromethoxy)Phenyl]Piperidine is a high-value, fluorinated piperidine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique trifluoromethoxy-phenyl moiety, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or complex molecules in asymmetric catalysis and material science.
• Life Science Research: Employed as a reference standard or biochemical tool in pharmacological studies and diagnostic assay development.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing specialized fluorinated compounds with high added value.

Basic Information

Product Name	2-[4-(Trifluoromethoxy)Phenyl]Piperidine
CAS No.	1019345-74-4
Molecular Formula	C12H14F3NO
Molecular Weight	245.24 g/mol
Synonyms	2-(4-(Trifluoromethoxy)phenyl)piperidine; 1-(4-(Trifluoromethoxy)phenyl)-2-piperidine; 4-(Trifluoromethoxy)phenyl-2-piperidine; 2-(4-Trifluoromethoxyphenyl)piperidine; α-(4-Trifluoromethoxyphenyl)piperidine; Piperidine, 2-[4-(trifluoromethoxy)phenyl]-; 1019345-74-4
EINECS	Contact for details

Quality Control

Our 2-[4-(Trifluoromethoxy)Phenyl]Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.