Description

(4-Methyl-1-Piperazinyl)(4-Piperidinyl)Methanonehydrochloride CAS NO 1018826-44-2 is a high-purity organic salt, specifically a hydrochloride derivative of a piperazine-piperidine ketone. This compound is a critical pharmaceutical intermediate valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, where its specific molecular scaffold is integral to the final drug's structure.
• Medicinal Chemistry Research: Serves as a versatile precursor for structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Bioconjugation & Probe Development: Utilized in the development of biochemical probes and labeled compounds for diagnostic and research applications.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial drug substances under GMP guidelines.

Basic Information

Product Name	(4-Methyl-1-Piperazinyl)(4-Piperidinyl)Methanonehydrochloride
CAS No.	1018826-44-2
Molecular Formula	C11H21N3O • HCl
Molecular Weight	247.77 g/mol (Free base: 211.31 g/mol)
Synonyms	4-(4-Methylpiperazine-1-carbonyl)piperidine hydrochloride; 1-[(4-Piperidinyl)carbonyl]-4-methylpiperazine hydrochloride; (4-Piperidinyl)[4-(methyl)-1-piperazinyl]methanone hydrochloride; 4-Methyl-1-piperazinecarboxylic acid 4-piperidinyl ester hydrochloride; 4-Piperidinyl 4-methylpiperazine-1-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our (4-Methyl-1-Piperazinyl)(4-Piperidinyl)Methanonehydrochloride is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Our quality commitment ensures traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.