Description

tert-Butyl 4-(1-Aminopropan-2-Yl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a Boc-protected amine and a secondary amine, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Peptidomimetic Synthesis: Used to introduce constrained piperazine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of tool compounds and probes for studying biological pathways and protein interactions.
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides.
• Material Science: Building block for functional polymers and dendrimers with specific chemical properties.

Basic Information

Product Name	tert-Butyl 4-(1-Aminopropan-2-Yl)Piperazine-1-Carboxylate
CAS No.	1018248-96-8
Molecular Formula	C12H25N3O2
Molecular Weight	243.35 g/mol
Synonyms	1-Boc-4-(2-Aminopropyl)piperazine; 2-(4-Boc-piperazin-1-yl)propylamine; tert-Butyl 4-(2-aminopropyl)piperazine-1-carboxylate; 1-(2-Aminopropyl)-4-(tert-butoxycarbonyl)piperazine; 4-(1-Aminopropan-2-yl)piperazine-1-carboxylic acid tert-butyl ester; 1018248-96-8; Boc-4-(2-aminopropyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1-Aminopropan-2-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.