Description

1-(3-Chloro-2-Pyridinyl)-3-Methylpiperazine is a high-purity, versatile heterocyclic building block and intermediate of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a chloropyridine moiety with a methylpiperazine ring, making it a critical precursor for the development of novel active compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic small molecules.
• Agrochemical Research: Serves as a crucial precursor in the development of new pesticides, herbicides, and fungicides, leveraging its heterocyclic scaffold.
• Chemical Synthesis: Used in academic and industrial R&D for constructing complex piperazine-containing compounds and exploring novel chemical spaces.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis and scale-up projects.

Basic Information

Product Name	1-(3-Chloro-2-Pyridinyl)-3-Methylpiperazine
CAS No.	1017789-43-3
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	3-Methyl-1-(3-chloro-2-pyridinyl)piperazine; 1-(3-Chloro-pyridin-2-yl)-3-methyl-piperazine; 3-Methyl-1-(3-chloropyridin-2-yl)piperazine; 1-(3-Chloro-2-pyridyl)-3-methylpiperazine; 2-(3-Methylpiperazin-1-yl)-3-chloropyridine; 3-Chloro-2-(3-methyl-1-piperazinyl)pyridine; 1017789-43-3
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-2-Pyridinyl)-3-Methylpiperazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and other relevant methods. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.