Description

tert-Butyl 4-(2-Formyl-4-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular scaffold combining formyl, nitro, and protected piperazine functionalities. This compound is of critical importance for research and development chemists engaged in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical companies and contract research organizations (CROs) focused on developing new therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncology.
• Chemical Synthesis Research: Used in academic and industrial R&D laboratories for exploring new synthetic pathways and creating libraries of novel chemical entities for biological screening.
• API Development: Integral in the development of Active Pharmaceutical Ingredients (APIs) that require a functionalized tetrahydro-1(2H)-pyrazinecarboxylate core structure.
• Peptidomimetic Chemistry: Acts as a precursor or scaffold in the design and synthesis of peptidomimetics, which are molecules that mimic the biological activity of peptides.
• Ligand Synthesis for Drug Discovery: Utilized in the preparation of specialized ligands and molecular probes for pharmacological and biochemical studies.

Basic Information

Product Name	tert-Butyl 4-(2-Formyl-4-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	1017782-93-2
Molecular Formula	C16H21N3O5
Molecular Weight	335.36 g/mol
Synonyms	1-Boc-4-(2-formyl-4-nitrophenyl)piperazine; tert-Butyl 4-(2-formyl-4-nitrophenyl)piperazine-1-carboxylate; 4-(2-Formyl-4-nitrophenyl)-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-formyl-4-nitrophenyl)piperazine; 4-(2-Formyl-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester; Boc-4-(2-formyl-4-nitrophenyl)piperazine; 1017782-93-2; tert-Butyl 4-(2-formyl-4-nitrophenyl)-1,2,3,6-tetrahydropyridine-1-carboxylate (related structure)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Formyl-4-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.