Description

5-(4-Boc-Piperazino)-2-Nitroanisole is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to modify pharmacokinetic properties.
• API Development: Serves as a precursor in multi-step synthetic routes for the production of complex, high-value active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	5-(4-Boc-Piperazino)-2-Nitroanisole
CAS No.	1017782-79-4
Molecular Formula	C16H23N3O5
Molecular Weight	337.37 g/mol
Synonyms	1-Boc-4-(5-Methoxy-2-nitrophenyl)piperazine; tert-Butyl 4-(5-methoxy-2-nitrophenyl)piperazine-1-carboxylate; 5-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-nitroanisole; 2-Nitro-5-(1-Boc-piperazin-4-yl)anisole; 1-(tert-Butoxycarbonyl)-4-(5-methoxy-2-nitrophenyl)piperazine
EINECS	Contact for details

Quality Control

Our 5-(4-Boc-Piperazino)-2-Nitroanisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Our quality commitment supports applications requiring high-purity intermediates for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.