Description

4-(3-Oxo-3-Phenyl-Propionyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and tert-butyl ester functional groups. This compound is essential for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories for creating novel therapeutic agents, including potential candidates for central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry R&D: Used in research laboratories for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitor candidates.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptide-like compounds with enhanced stability and bioavailability.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
• Chemical Library Development: Used to create diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	4-(3-Oxo-3-Phenyl-Propionyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1017781-53-1
Molecular Formula	C19H25NO4
Molecular Weight	331.41 g/mol
Synonyms	1-Boc-4-(3-oxo-3-phenylpropanoyl)piperidine; tert-Butyl 4-(3-oxo-3-phenylpropanoyl)piperidine-1-carboxylate; 4-(3-Oxo-3-phenylpropionyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-oxo-3-phenylpropanoyl)piperidine; BOC-Piperidine-4-(3-oxo-3-phenylpropanoate); 1017781-53-1; 4-(3-Oxo-3-phenyl-1-oxopropyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Oxo-3-Phenyl-Propionyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.