Description

6-Bromo-5-Chloropyrazine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand & Catalyst Development: Serves as a precursor for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A building block for functionalized polymers and organic electronic materials due to the pyrazine core.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bio-conjugates for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Bromo-5-Chloropyrazine-2-Carboxylic Acid
CAS No.	1017604-40-8
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	5-Chloro-6-bromopyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 6-bromo-5-chloro-; 6-Bromo-5-chloro-2-pyrazinecarboxylic acid; 6-Bromo-5-chloropyrazine-2-carboxylic acid; 1017604-40-8; 5-Chloro-6-bromo-2-pyrazinecarboxylic acid; Bromochloro pyrazine carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloropyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.