Description

1-[1-(Cyclopropylmethyl)-4-Piperidinyl]Methanamine (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate featuring a unique piperidine scaffold with a cyclopropylmethyl substituent. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential role in modulating biological targets. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. The free base form offers versatility for further synthetic modifications under a variety of reaction conditions.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates targeting central nervous system (CNS) disorders, pain management, or other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged piperidine structure.
• Chemical Synthesis: Serves as a precursor for the preparation of more complex molecules, including potential receptor ligands or enzyme inhibitors.
• Biochemical Research: May be utilized in the development of biochemical probes and tools for studying biological pathways and protein interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	1-[1-(Cyclopropylmethyl)-4-Piperidinyl]Methanamine (Saltdata: Free)
CAS No.	1017400-92-8
Molecular Formula	C10H20N2
Molecular Weight	168.28 g/mol
Synonyms	1-((1-(Cyclopropylmethyl)piperidin-4-yl)methyl)amine; 1-(Cyclopropylmethyl)-4-(aminomethyl)piperidine; 4-Piperidinemethanamine, 1-(cyclopropylmethyl)-; 1-(Cyclopropylmethyl)-4-piperidinylmethanamine; 1-(1-Cyclopropylmethyl-piperidin-4-yl)-methylamine; (1-(Cyclopropylmethyl)piperidin-4-yl)methanamine; 1-(Cyclopropylmethyl)-4-(aminomethyl)piperidine, free base
EINECS	Contact for details

Quality Control

Our 1-[1-(Cyclopropylmethyl)-4-Piperidinyl]Methanamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.