Description

(3-Oxopiperazin-1-Yl)Acetonitrile is a high-purity pharmaceutical intermediate and versatile chemical building block. This compound is valued for its piperazine-based heterocyclic structure, which is a key pharmacophore in the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for synthesizing novel compounds and complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex piperazine derivatives and other nitrogen-containing heterocycles.
• Bioconjugation & Linker Chemistry: The nitrile and carbonyl functional groups make it suitable for use in linker molecules for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Chemical Biology Probe Development: Employed in medicinal chemistry for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	(3-Oxopiperazin-1-Yl)Acetonitrile
CAS No.	1016823-35-0
Molecular Formula	C6H9N3O
Molecular Weight	139.16 g/mol
Synonyms	2-(3-Oxopiperazin-1-yl)acetonitrile; 1-(Cyanomethyl)-3-oxopiperazine; 2-(3-Oxopiperazin-1-yl)ethanenitrile; 1-(Cyanomethyl)piperazin-2-one; (3-Oxo-1-piperazinyl)acetonitrile; 1-Piperazineacetonitrile, 3-oxo-; 3-Oxo-1-piperazineacetonitrile
EINECS	Contact for details

Quality Control

Our (3-Oxopiperazin-1-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and commercial projects with material suitable for research use, pilot-scale synthesis, and can provide documentation to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.