Description

1-(3,3-Dimethyl-1-Oxobutyl)-4-Piperidinone is a high-purity organic intermediate featuring a piperidinone core functionalized with a pivaloyl-like ketone side chain. This compound matters as a versatile and critical building block for the synthesis of more complex pharmaceutical and agrochemical molecules, enabling the introduction of sterically hindered, lipophilic moieties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, where its structural motif can contribute to the desired biological activity and stability.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating specialty chemicals, ligands, and catalysts.
• Academic & Industrial Research: Serves as a valuable starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	1-(3,3-Dimethyl-1-Oxobutyl)-4-Piperidinone
CAS No.	1016705-45-5
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	4-Piperidinone, 1-(3,3-dimethyl-1-oxobutyl)-; 1-Pivaloyl-4-piperidinone; 1-(3,3-Dimethylbutanoyl)piperidin-4-one; 1-(Pivaloyl)piperidin-4-one; 1-(2,2-Dimethylpropionyl)piperidin-4-one; 4-Oxo-1-pivaloylpiperidine; 1-(Tert-butylcarbonyl)-4-piperidinone
EINECS	Contact for details

Quality Control

Our 1-(3,3-Dimethyl-1-Oxobutyl)-4-Piperidinone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.