Description

3-(4-Methylpiperazine-1-Sulfonyl)Benzonitrile is a high-purity organic intermediate featuring a benzonitrile core functionalized with a methylpiperazine sulfonyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and kinase inhibition.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its sulfonamide functionality.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Applications: Potential monomer or additive for advanced polymers with specific electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	3-(4-Methylpiperazine-1-Sulfonyl)Benzonitrile
CAS No.	1016672-98-2
Molecular Formula	C12H15N3O2S
Molecular Weight	265.33 g/mol
Synonyms	3-[(4-Methyl-1-piperazinyl)sulfonyl]benzonitrile; 3-(4-Methylpiperazine-1-sulfonyl)benzonitrile; Benzonitrile, 3-[(4-methyl-1-piperazinyl)sulfonyl]-; 3-(N-Methylpiperazinosulfonyl)benzonitrile; 1-[(3-Cyanophenyl)sulfonyl]-4-methylpiperazine; 3-Cyano-N-(4-methylpiperazin-1-yl)benzenesulfonamide; 1016672-98-2
EINECS	Contact for details

Quality Control

Our 3-(4-Methylpiperazine-1-Sulfonyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades, including pharmaceutical intermediates grade, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.