Description

2-Phenyl-1-(Piperazin-1-yl)butan-1-one is a high-purity synthetic organic compound featuring a phenylbutanone core linked to a piperazine moiety. This specific molecular architecture makes it a valuable pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules with potential therapeutic applications, particularly in central nervous system (CNS) and other specialty drug candidates.
• Chemical Research & Development: Serves as a critical building block for medicinal chemists exploring new chemical entities and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Used in the production of high-value, low-volume specialty chemicals for advanced material science and agrochemical research.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	2-Phenyl-1-(Piperazin-1-yl)butan-1-one
CAS No.	1016503-45-9
Molecular Formula	C14H20N2O
Molecular Weight	232.32 g/mol
Synonyms	1-(2-Phenylbutanoyl)piperazine; 2-Phenyl-1-piperazin-1-ylbutan-1-one; 2-Phenylbutyropiperazine; Butyrophenone, 2-phenyl-1-piperazinyl-; α-Ethylbenzenepropanoic acid piperazide
EINECS	Contact for details

Quality Control

Our 2-Phenyl-1-(Piperazin-1-yl)butan-1-one is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.