Description

1,4-Piperidinedicarboxylic Acid, 4-(Aminomethyl)-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester is a high-purity, functionalized piperidine derivative serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its unique bifunctional structure, featuring both a protected amino group and ester functionalities, enabling precise molecular construction. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex active pharmaceutical ingredients (APIs) and novel bioactive compounds. CAS No. 1016258-69-7.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its piperidine scaffold.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker in the design of molecular probes and enzyme inhibitors for target validation studies.
• Peptidomimetics & Conformational Restriction: The piperidine core is utilized to introduce conformational constraints into peptide analogs, enhancing stability and bioavailability.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	1,4-Piperidinedicarboxylic Acid, 4-(Aminomethyl)-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester
CAS No.	1016258-69-7
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	4-(Aminomethyl)-1-(tert-butyl) 4-ethyl piperidine-1,4-dicarboxylate; tert-Butyl 4-(aminomethyl)-4-(ethoxycarbonyl)piperidine-1-carboxylate; 1-Boc-4-(aminomethyl)-4-(ethoxycarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(aminomethyl)-4-(ethoxycarbonyl)piperidine; 4-(Aminomethyl)-1-Boc-4-carbethoxy piperidine; 4-Carbethoxy-4-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester; 1,4-Piperidinedicarboxylic acid, 4-(aminomethyl)-, 1-(1,1-dimethylethyl) 4-ethyl ester; 4-(Aminomethyl)-4-(ethoxycarbonyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1,4-Piperidinedicarboxylic Acid, 4-(Aminomethyl)-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to research-grade and cGMP standards to meet the specific requirements of preclinical and clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.