Description

Ethyl 2-Fluoro-5H-Pyrrolo[2,3-B]Pyrazine-6-Carboxylate is a high-value fluorinated heterocyclic building block, specifically a pyrrolopyrazine derivative, essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, offering a strategic fluorine atom and a versatile ester group for further functionalization. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including kinase inhibitors and other biologically relevant scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Kinase Inhibitor Development: Used to construct the core scaffold for potential protein kinase inhibitors due to the pyrrolopyrazine structure.
• Agrochemical Research: Serves as a key intermediate in the discovery of new herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the creation of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Potential precursor for the synthesis of specialty chemicals and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	Ethyl 2-Fluoro-5H-Pyrrolo[2,3-B]Pyrazine-6-Carboxylate
CAS No.	1016241-85-2
Molecular Formula	C9H8FN3O2
Molecular Weight	209.18 g/mol
Synonyms	Ethyl 2-fluoro-5H-pyrrolo[2,3-b]pyrazine-6-carboxylate; 2-Fluoro-5H-pyrrolo[2,3-b]pyrazine-6-carboxylic acid ethyl ester; 6-Ethoxycarbonyl-2-fluoro-5H-pyrrolo[2,3-b]pyrazine; 2-Fluoro-5H-pyrrolo[2,3-b]pyrazine-6-carboxylic acid, ethyl ester; Ethyl 2-fluoropyrrolo[2,3-b]pyrazine-6-carboxylate; 1016241-85-2; FPPE; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-5H-Pyrrolo[2,3-B]Pyrazine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.