Description

2-Fluoro-5H-Pyrrolo[3,2-B]Pyrazine-6-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical research and agrochemical discovery laboratories need this specialized chemical for its unique reactivity profile and the ability to introduce fluorine atoms into target molecules, a critical strategy for modulating bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Biology Probe Development: Employed to synthesize fluorinated analogs of natural products or biochemical probes for studying enzyme mechanisms and binding interactions.
• Contract Research & Development (CRO/CMO): Supplied to research organizations engaged in custom synthesis and process development for clients.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Item	Details
Product Name	2-Fluoro-5H-Pyrrolo[3,2-B]Pyrazine-6-Carboxylic Acid
CAS No.	1016241-84-1
Molecular Formula	C7H4FN3O2
Molecular Weight	181.12 g/mol
Synonyms	2-Fluoro-5H-pyrrolo[3,2-b]pyrazine-6-carboxylic acid; 6-Carboxy-2-fluoro-5H-pyrrolo[3,2-b]pyrazine; 2-Fluoro-6-carboxy-5H-pyrrolo[3,2-b]pyrazine; 1016241-84-1; 2-Fluoro-5H-pyrrolo[3,2-b]pyrazine-6-carboxylate; 2-Fluoropyrrolopyrazine-6-carboxylic acid; Pyrrolo[3,2-b]pyrazine-6-carboxylic acid, 2-fluoro-5H-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5H-Pyrrolo[3,2-B]Pyrazine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.