Description

2-Methyltetrahydro-2H-pyrazino[1,2-a]pyrazine-1,4(3H,6H)-dione (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. Pharmaceutical R&D and manufacturing organizations need this precise chemical building block to develop and scale up novel drug candidates, ensuring process reliability and final product quality. Its availability in free form offers greater flexibility in downstream synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety in the research and development of new chemical entities (NCEs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for GMP manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	2-Methyltetrahydro-2H-pyrazino[1,2-a]pyrazine-1,4(3H,6H)-dione (Saltdata: Free)
CAS No.	1009597-84-5
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	2-Methyl-1,2,3,4,6,7-hexahydropyrazino[1,2-a]pyrazine-1,4-dione; 2-Methylhexahydropyrazino[1,2-a]pyrazine-1,4-dione; 1009597-84-5; 2-Methyl-1,2,3,4,6,7-hexahydro-pyrazino[1,2-a]pyrazine-1,4-dione; 2-Methyl-1,2,3,4,6,7-hexahydropyrazino[1,2-a]pyrazine-1,4-dione (free base); 2-Methyltetrahydro-2H-pyrazino[1,2-a]pyrazine-1,4(3H,6H)-dione free base
EINECS	Contact for details

Quality Control

Our 2-Methyltetrahydro-2H-pyrazino[1,2-a]pyrazine-1,4(3H,6H)-dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with ICH Q7 guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.