Description

n-[(2-Ethyl-3-Oxo-1-Piperazinyl)Carbonothioyl]-4-Biphenylcarboxamide is a specialized organic compound with the CAS number 1009552-13-9. This high-purity chemical intermediate is critical for research and development in advanced pharmaceutical synthesis, particularly for creating novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for its role in constructing complex molecular architectures.

Application

This compound serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the research and synthesis of new therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new API candidates.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.
• Chemical Biology Probes: Potential use in developing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	n-[(2-Ethyl-3-Oxo-1-Piperazinyl)Carbonothioyl]-4-Biphenylcarboxamide
CAS No.	1009552-13-9
Molecular Formula	C20H21N3O2S
Molecular Weight	367.47 g/mol
Synonyms	4-Biphenylcarboxamide, N-[(2-ethyl-3-oxo-1-piperazinyl)carbonothioyl]-; 1-(4-Biphenylcarbonyl)-3-(2-ethyl-3-oxopiperazin-1-yl)thiourea; N-(2-Ethyl-3-oxopiperazine-1-carbonothioyl)biphenyl-4-carboxamide; 1009552-13-9; UNII-7K8Q5F8V4I; Biphenyl-4-carboxylic acid [N'-(2-ethyl-3-oxo-piperazin-1-yl)-thioureido]-amide
EINECS	Contact for details

Quality Control

Our n-[(2-Ethyl-3-Oxo-1-Piperazinyl)Carbonothioyl]-4-Biphenylcarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.