Description

Methyl trans-6-Methylpiperidine-3-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant intermediate in the form of a stable hydrochloride salt. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for API manufacturing.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and target validation.

Basic Information

Product Name	Methyl trans-6-Methylpiperidine-3-Carboxylate Hydrochloride
CAS No.	1009376-86-6
Molecular Formula	C9H18ClNO2
Molecular Weight	207.70 g/mol
Synonyms	trans-Methyl 6-methylnipecotate hydrochloride; Methyl (3R,6R)-6-methylpiperidine-3-carboxylate hydrochloride; 6-Methylnipecotic acid methyl ester hydrochloride; Methyl 6-methyl-3-piperidinecarboxylate hydrochloride (trans); 3-Piperidinecarboxylic acid, 6-methyl-, methyl ester, hydrochloride, (3R,6R)-; Methyl trans-6-methyl-3-piperidinecarboxylate HCl; trans-6-Methylpiperidine-3-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl trans-6-Methylpiperidine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.