Description

n-{[3,5-Difluoro-3'-(1H-1,2,4-Triazol-5-Yl)-[1,1'-Biphenyl]-4-Yl]Methyl}-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride is a high-purity, non-racemic chiral amine derivative designed for advanced pharmaceutical research and development. This compound matters as a sophisticated chemical building block and pharmacological reference standard for the synthesis of novel therapeutic agents. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly those focused on central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research-scale synthesis of potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point for structure-activity relationship (SAR) studies.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Probe Development: Utilized in the design and testing of compounds for target validation and mechanistic studies.
• Process Chemistry: Employed in the development and optimization of synthetic routes for complex molecules.
• Academic Research: Used in university and institutional labs for cutting-edge chemical and pharmacological investigations.

Basic Information

Product Name	n-{[3,5-Difluoro-3'-(1H-1,2,4-Triazol-5-Yl)-[1,1'-Biphenyl]-4-Yl]Methyl}-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride
CAS No.	1007578-24-6
Molecular Formula	C24H21F2N5·HCl
Molecular Weight	453.92 g/mol (Free base: 417.46 g/mol)
Synonyms	(S)-N-((3',5-Difluoro-3-(1H-1,2,4-triazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2,3-dihydro-1H-inden-2-amine hydrochloride; (S)-N-((3',5-Difluoro-3-(1H-1,2,4-triazol-5-yl)biphenyl-4-yl)methyl)-2,3-dihydro-1H-inden-2-amine hydrochloride; BMS-A; BMS-A Hydrochloride; BMS-A HCl; (S)-BMS-A Hydrochloride; (S)-N-((3',5-Difluoro-3-(1H-1,2,4-triazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-aminoindane hydrochloride
EINECS	Contact for details

Quality Control

Our n-{[3,5-Difluoro-3'-(1H-1,2,4-Triazol-5-Yl)-[1,1'-Biphenyl]-4-Yl]Methyl}-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride is manufactured under cGMP-like conditions suitable for research and development applications. Every batch undergoes rigorous analytical testing, including chiral purity determination, to ensure identity, potency, and purity. Comprehensive Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.