Description

tert-Butyl 4-(4-Bromophenethyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a Boc (tert-butoxycarbonyl) group and a 4-bromophenethyl side chain. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with piperazine-based pharmacophores.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies for CNS-targeted therapies.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development and validation of robust, scalable synthetic routes under GMP-like conditions.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Bioconjugation & Probe Development: The reactive bromophenyl group allows for further functionalization, making it useful for creating biochemical probes or labeled compounds.

Basic Information

Product Name	tert-Butyl 4-(4-Bromophenethyl)Piperazine-1-Carboxylate
CAS No.	1007209-94-0
Molecular Formula	C17H25BrN2O2
Molecular Weight	369.30 g/mol
Synonyms	1-Boc-4-(4-Bromophenethyl)piperazine; 4-(4-Bromophenethyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(2-(4-bromophenyl)ethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-bromophenethyl)piperazine; BOC-4-(4-Bromophenethyl)piperazine; 1007209-94-0; 4-(4-Bromophenethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-(4-Bromophenethyl)Piperazine-1-Carboxylate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and development needs. Certificates of Analysis (COA) with detailed HPLC/GC purity, NMR, and mass spectrometry data are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.