Description

(R)-5-Amino-Piperidin-2-One Hcl CAS NO 1003021-01-9 is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutics, particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of inhibitors targeting various proteases, which are relevant for treating conditions like hypertension and viral infections.
• Neurological Drug Discovery: Serves as a precursor in the research and synthesis of compounds targeting neurological receptors and pathways.
• Peptidomimetic Chemistry: Employed in the design and construction of peptidomimetics, which are molecules that mimic the structure and function of peptides.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in asymmetric catalytic reactions to introduce stereocenters.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	(R)-5-Amino-Piperidin-2-One Hcl
CAS No.	1003021-01-9
Molecular Formula	C5H11N2O•HCl
Molecular Weight	150.62 g/mol (Free base: 114.16 g/mol)
Synonyms	(R)-5-Aminopiperidin-2-one hydrochloride; (R)-2-Oxo-5-aminopiperidine hydrochloride; (R)-5-Amino-2-piperidinone hydrochloride; (R)-5-Azanylpiperidin-2-one hydrochloride; (R)-Amino-δ-valerolactam hydrochloride; (R)-5-Amino-2-piperidone HCl; (R)-5-Amino-δ-valerolactam hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-5-Amino-Piperidin-2-One Hcl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We employ advanced analytical techniques, including chiral HPLC and NMR, to verify identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.