Description

2-Bromo-5-Pyrrolidin-1-Ylpyrazine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile intermediate, enabling the construction of complex molecular architectures through its reactive bromine and pyrrolidine substituents. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in medicinal chemistry for creating targeted small molecule libraries.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific pyrazine-based scaffolds.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.
• Academic & Institutional Research: Used in university and institutional laboratories for fundamental research in organic chemistry and methodology development.

Basic Information

Product Name	2-Bromo-5-Pyrrolidin-1-Ylpyrazine
CAS No.	1001050-21-0
Molecular Formula	C8H10BrN3
Molecular Weight	228.09 g/mol
Synonyms	2-Bromo-5-(pyrrolidin-1-yl)pyrazine; 5-(Pyrrolidin-1-yl)-2-bromopyrazine; 2-Bromo-5-pyrrolidin-1-yl-pyrazine; Pyrazine, 2-bromo-5-(1-pyrrolidinyl)-; 1001050-21-0; 2-Bromo-5-(1-pyrrolidinyl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Pyrrolidin-1-Ylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full batch traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.