Description

Methyl 2-(4-(Phenyl(3-(Trifluoromethyl)Phenyl)Methyl)Piperazin-1-Yl)Acetate is a high-value, synthetically versatile piperazine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethylphenyl group, makes it particularly significant for developing compounds with enhanced metabolic stability and bioavailability. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Advanced Material Synthesis: Potential building block for specialty polymers or liquid crystals that require specific fluorinated aromatic components.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Methyl 2-(4-(Phenyl(3-(Trifluoromethyl)Phenyl)Methyl)Piperazin-1-Yl)Acetate
CAS No.	1000691-88-2
Molecular Formula	C21H23F3N2O2
Molecular Weight	392.42 g/mol
Synonyms	Methyl {4-[phenyl(3-(trifluoromethyl)phenyl)methyl]piperazin-1-yl}acetate; 1-[(3-Trifluoromethylphenyl)phenylmethyl]-4-(methoxycarbonylmethyl)piperazine; Methyl 2-[4-[[3-(trifluoromethyl)phenyl]-phenylmethyl]-1-piperazinyl]acetate; Methyl (4-((3-(trifluoromethyl)phenyl)(phenyl)methyl)piperazin-1-yl)acetate; 1000691-88-2; CAS 1000691-88-2
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(4-(Phenyl(3-(Trifluoromethyl)Phenyl)Methyl)Piperazin-1-Yl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, with each shipment. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.