Description

Hexahydropyrrolo[1,2-A]Pyrazin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the class of fused bicyclic heterocycles. This compound is of significant commercial interest due to its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, particularly those targeting the central nervous system.
• API Synthesis: Used as a key scaffold for constructing the core structure of potential new chemical entities (NCEs) in medicinal chemistry research.
• Process Chemistry: Employed in route scouting and scale-up processes for the efficient and cost-effective manufacturing of target compounds.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and clinical trial material production.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	Hexahydropyrrolo[1,2-A]Pyrazin-4(1H)-One
CAS No.	1000577-63-8
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	1,4,5,6,7,8-Hexahydropyrrolo[1,2-a]pyrazin-4-one; Pyrrolo[1,2-a]pyrazin-4(1H)-one, hexahydro-; Hexahydro-1H-pyrrolo[1,2-a]pyrazin-4-one; 4-Oxo-hexahydro-pyrrolo[1,2-a]pyrazine; Fused bicyclic pyrrolopyrazinone intermediate
EINECS	Contact for details

Quality Control

Our Hexahydropyrrolo[1,2-A]Pyrazin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.