Description

2-(4-Bromophenyl)-2-(Piperazin-1-Yl)Acetonitrile is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical manufacturers developing new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Reagent: Serves as a precursor for the introduction of the 2-(piperazin-1-yl)acetonitrile moiety into more complex molecular architectures.
• Chemical Library Development: A valuable scaffold for creating diverse compound libraries for high-throughput screening in drug discovery.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Product Name	2-(4-Bromophenyl)-2-(Piperazin-1-Yl)Acetonitrile
CAS No.	1000406-20-1
Molecular Formula	C12H14BrN3
Molecular Weight	280.17 g/mol
Synonyms	2-(4-Bromophenyl)-2-(piperazin-1-yl)ethanenitrile; 2-(4-Bromophenyl)-2-(1-piperazinyl)acetonitrile; 2-(4-Bromophenyl)-2-(piperazin-1-yl)acetonitrile; 2-(4-Bromophenyl)-2-piperazin-1-ylacetonitrile; α-(4-Bromophenyl)-α-(1-piperazinyl)acetonitrile; 1000406-20-1; (4-Bromophenyl)(piperazin-1-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-2-(Piperazin-1-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This compound is moisture-sensitive (hygroscopic); ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.