Description

1-(2-{[5-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Ethyl)Piperazine is a high-value, multi-functional heterocyclic compound featuring a piperazine core linked to a trifluoromethyl-substituted pyridine moiety via an ethoxy spacer. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex bioactive molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Serves as a crucial building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis and material science applications.
• Chemical Biology Research: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular framework.

Basic Information

Product Name	1-(2-{[5-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Ethyl)Piperazine
CAS No.	1000339-99-0
Molecular Formula	C12H16F3N3O
Molecular Weight	275.27 g/mol
Synonyms	2-({2-[4-(5-Trifluoromethyl-2-pyridyloxy)ethyl]-1-piperazinyl}ethyl 5-trifluoromethyl-2-pyridyl ether; 1-[2-({5-(Trifluoromethyl)-2-pyridinyl}oxy)ethyl]piperazine; 2-({2-[4-(5-Trifluoromethyl-2-pyridyloxy)ethyl]-1-piperazinyl}ethyl 5-trifluoromethyl-2-pyridyl ether; 1-(2-((5-(Trifluoromethyl)pyridin-2-yl)oxy)ethyl)piperazine; 1-[2-[[5-(Trifluoromethyl)-2-pyridinyl]oxy]ethyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-{[5-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Ethyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.