Description

Sulopenem Etzadroxil is an advanced oral prodrug of the penem antibiotic sulopenem, designed to enhance bioavailability. This compound is critical for the development of next-generation antibacterial agents targeting multidrug-resistant infections. It is primarily required by pharmaceutical R&D departments and manufacturers engaged in the synthesis of novel antibiotic formulations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of the active pharmaceutical ingredient (API) Sulopenem.
• Antibacterial Drug Development: Used in research and development of new oral antibiotic therapies.
• Clinical Trial Material: Serves as a critical raw material for producing batches for preclinical and clinical studies.
• Combinatorial Chemistry: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies of β-lactam antibiotics.
• Reference Standard: Acts as a high-purity standard for analytical method development and quality control testing.

Basic Information

Product Name	Sulopenem Etzadroxil
CAS No.	1000296-70-7
Molecular Formula	C21H27N5O7S2
Molecular Weight	533.60 g/mol
Synonyms	(1R,5S,6S)-2-[(3S,5S)-5-[(S)-1-Hydroxyethyl]-3-[(R)-1-(1,3-thiazolidin-2-yl)ethoxy]-4-oxo-1-azabicyclo[3.2.0]hept-2-en-2-yl]sulfanyl-6-[(R)-1-hydroxyethyl]-1-methyl-1-carbapen-2-em-3-carboxylic acid; PF-03709270; Etzadroxil Prodrug of Sulopenem; (4R,5S,6S)-3-[[(3S,5S)-5-[(1S)-1-Hydroxyethyl]-3-[[(2R)-2-(1,3-thiazolidin-2-yl)-1-oxoethoxy]methyl]-4-oxo-1-azabicyclo[3.2.0]hept-2-en-2-yl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Sulopenem Etzadroxil is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.