Description

Benzyl 4-(n-(tert-Butoxycarbonyl)Sulfamoyl)Piperazine-1-Carboxylate is a sophisticated, multi-functional piperazine derivative designed for advanced synthetic chemistry. This compound serves as a critical protected intermediate and building block in the synthesis of complex molecules, offering chemists precise control over molecular architecture. It is primarily utilized by pharmaceutical research and development organizations and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Sulfonamide-Based API Synthesis: Used to introduce the protected sulfamoyl-piperazine moiety into complex molecular scaffolds for the development of new sulfonamide-class therapeutics.
• Peptidomimetic & PROTAC Development: Serves as a versatile linker or functional group in the design of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs).
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific, high-purity intermediates.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	Benzyl 4-(n-(tert-Butoxycarbonyl)Sulfamoyl)Piperazine-1-Carboxylate
CAS No.	1000018-21-2
Molecular Formula	C17H25N3O6S
Molecular Weight	399.46 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-[(tert-butoxycarbonyl)sulfamoyl]piperazine; Benzyl 4-[(tert-Butoxycarbonylamino)sulfonyl]piperazine-1-carboxylate; tert-Butyl N-({4-[(benzyloxy)carbonyl]piperazin-1-yl}sulfonyl)carbamate; Boc-Sulfamoyl-Piperazine-Cbz; N-Boc-Sulfamoyl-Piperazine-N'-Cbz; (Benzyloxycarbonyl)piperazinylsulfamoyl tert-butyl carbamate; 4-(N-Boc-sulfamoyl)piperazine-1-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our production of Benzyl 4-(n-(tert-Butoxycarbonyl)Sulfamoyl)Piperazine-1-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with client specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.